Article
Impact of apo E phenotype on the regulation of cholesterol metabolism.
Annals of medicine - 1 Apr 1991
Miettinen T A
Abstract excerpt
Cholesterol absorption was positively related to the apo E subscript in middle aged men on their normal home diet. The apo E subscript (e.g. E2/2 = 1, E2/3 = 2, E2/4 = 3...) was negatively associated with cholesterol synthesis and fractional removal of LDL apo B and positively with the total and LDL cholesterol and LDL apo B concentrations. Cholesterol elimination, especially as bile acids, was most effective in...
Topics
- Absorption
- Alleles
- Apolipoproteins B
- Apolipoproteins E
- Cholesterol
- Cholesterol, Dietary
- Cholesterol, LDL
- Dietary Fats
- Humans
- Hyperlipoproteinemia Type II
- Male
- Phenotype