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Article

Transcriptional modification by a CASK-interacting nucleosome assembly protein.

Neuron - 8 Apr 2004

Wang Guey-Shin, Hong Chen-Jei, Yen Tsen-Yann, Huang Hsin-Yi, Ou Yvonne, Huang Tzyy-Nan, Jung Wei-Gang, Kuo Ting-Yu, Sheng Morgan, Wang Ting-Fang, Hsueh Yi-Ping

Abstract excerpt

CASK acts as a coactivator for Tbr-1, an essential transcription factor in cerebral cortex development. Presently, the molecular mechanism of the CASK coactivation effect is unclear. Here, we report that CASK binds to another nuclear protein, CINAP, which binds histones and facilitates nucleosome assembly. CINAP, via its interaction with CASK, forms a complex with Tbr-1, regulating expression of the genes...

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Source

Identifiers

PMID: 15066269
DOI: 10.1016/s0896-6273(04)00139-4

Genes

CASK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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