Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential regulation of the human sodium/iodide symporter gene promoter in papillary thyroid carcinoma cell lines and normal thyroid cells.

Endocrinology - 1 Aug 2001

Kogai T, Hershman J M, Motomura K, Endo T, Onaya T, Brent G A

Abstract excerpt

The absence of TSH-stimulated radioiodide uptake in differentiated thyroid cancer is associated with a high recurrence rate and reduced survival. We studied regulation of the sodium/iodide symporter gene in human papillary thyroid cancer cell lines (BHP) and primary human thyroid cells. BHP cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Papillary
Share to Iodides
Share to Paired Box Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PAX8 Transcription Factor

Share to Symporters

Share to Thyroid Gland

Share to Thyroid Neoplasms

Share to Thyroid Nuclear Factor 1

Source

Identifiers

PMID: 11459780
DOI: 10.1210/endo.142.8.8344

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11459780-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential regulation of the human sodium/iodide symporter gene promoter in papillary thyroid carcinoma cell lines and normal thyroid cells.PMID 11459780Read ↗

A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3',5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells.Semantic proximity Read ↗

Iodide Symporter Gene Expression in Human Thyroid TumorsSemantic proximity Read ↗

A homozygous missense mutation of the sodium/iodide symporter gene causing iodide transport defect.Semantic proximity Read ↗

Histone deacetylation of NIS promoter underlies BRAF V600E-promoted NIS silencing in thyroid cancer.Semantic proximity Read ↗

Different expression of TSH receptor and NIS genes in thyroid cancer: role of epigeneticsSemantic proximity Read ↗

Expression of the Na+/I- Symporter Gene in Human Thyroid Tumors: A Comparison Study with Other Thyroid-Specific GenesSemantic proximity Read ↗

Novel, missense and loss-of-function mutations in the sodium/iodide symporter gene causing iodide transport defect in three Japanese patients.Semantic proximity Read ↗

Induction of Thyroid Gene Expression and Radioiodine Uptake in Thyroid Cancer Cells by Targeting Major Signaling PathwaysSemantic proximity Read ↗

Absence of sodium/iodide symporter gene mutations in differentiated human thyroid carcinomas.Semantic proximity Read ↗

Expression, Exon-Intron Organization, and Chromosome Mapping of the Human Sodium Iodide SymporterSemantic proximity Read ↗

Expression, Exon-Intron Organization, and Chromosome Mapping of the Human Sodium Iodide SymporterSemantic proximity Read ↗

Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.