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Article

Evolutionary divergence of thyrotropin receptor structure.

Molecular genetics and metabolism - 1 Apr 2004

Knudsen Bjarne, Farid Nadir R

Abstract excerpt

The availability of 18 thyrotropin receptor (TSHR) sequences, including two recent entries for primates and seven from fish, have allowed us to investigate diversification of residues or domains during evolution. We used a likelihood ratio test for evolutionary rate shifts [Proc. Natl. Acad. Sci. 98 (2001) 14512] using LH/CGR sequences as an out-group. At each residue in the alignment, a statistical test was...

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Source

Identifiers

PMID: 15059620
DOI: 10.1016/j.ymgme.2004.01.010

Genes

TSHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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