Article
Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia.
Hepatology (Baltimore, Md.) - 1 Apr 2004
Zhang Dong-Yi, Sabla Gregg, Shivakumar Pranavkumar, Tiao Greg, Sokol Ronald J, Mack Cara, Shneider Benjamin L, Aronow Bruce, Bezerra Jorge A
Abstract excerpt
The molecular basis for the embryonic and perinatal clinical forms of biliary atresia is largely undefined. In this study, we aimed to: 1) determine if the clinical forms can be differentiated at the transcriptional level, and 2) search for molecular mechanisms underlying phenotypic differences. To this end, we generated biotinylated cRNA probes from livers of age-matched infants with the embryonic (n = 5) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.