Article
Platelet monoamine oxidase activity in subjects tested for Huntington's disease gene mutation.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Apr 2004
Markianos M, Panas M, Kalfakis N, Vassilopoulos D
Abstract excerpt
Monoamine oxidase activity (MAO) has been related to neuronal damage, since the oxidative deamination of biogenic amines produces free radicals that may enhance oxidative stress. Elevated enzyme activities in brain (MAO-A and MAO-B forms) and in platelets (MAO-B form) have been reported in several degenerative diseases, indicating that MAO activity may be involved in the disease progression. We estimated platelet...
Topics
- Antipsychotic Agents
- Base Sequence
- Blood Platelets
- DNA Primers
- Female
- Haloperidol
- Humans
- Huntington Disease
- Isoenzymes
- Male
- Monoamine Oxidase
- Mutation
- Reference Values
