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Article

CD45 variant alleles: possibly increased frequency of a novel exon 4 CD45 polymorphism in HIV seropositive Ugandans.

Immunogenetics - 1 May 2004

Stanton Tara, Boxall Sally, Bennett Andrea, Kaleebu Pontiano, Watera Christine, Whitworth Jimmy, French Neil, Dawes Ritu, Hill Adrian V S, Bodmer Walter, Beverley Peter C L, Tchilian Elma Z

Abstract excerpt

The CD45 (leucocyte common) antigen is a haemopoietic cell specific tyrosine phosphatase essential for antigen receptor signalling in lymphocytes, and expression of different CD45 isoforms is associated with distinct functions. Here we describe a novel polymorphism in exon 4 (A54G) of the gene encoding CD45 (PTPRC) that results in an amino acid substitution of Thr-19 to Ala in exon 4. The 54G allele was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15057492
DOI: 10.1007/s00251-004-0668-z

Genes

PTPRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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