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Article

A point mutation in CD45 may be associated with an increased risk of HIV-1 infection.

AIDS (London, England) - 28 Sept 2001

Tchilian E Z, Wallace D L, Dawes R, Imami N, Burton C, Gotch F, Beverley P C

Abstract excerpt

The CD45 antigen is essential for normal antigen receptor-mediated signalling in lymphocytes, and different patterns of splicing of CD45 are associated with distinct functions in lymphocytes. Here we show that abnormal CD45 splicing caused by a C77G transversion in exon A of the gene encoding CD4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11579257
DOI: 10.1097/00002030-200109280-00024

Genes

PTPRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11579257-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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