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Article

Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates.

The Journal of antimicrobial chemotherapy - 1 May 2004

Jones Ronald N, Moet Gary J, Sader Helio S, Fritsche Thomas R

Abstract excerpt

OBJECTIVES: To evaluate the potency of a novel peptide deformylase inhibitor, NVP PDF-713, against Gram-positive organisms having resistances to linezolid or quinupristin/dalfopristin. MATERIALS AND METHODS: A total of 45 strains from three genera (six species groups) were tested by reference broth microdilution methods. The mechanism of resistance to the oxazolidinone was determined by sequencing of the gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15056649
DOI: 10.1093/jac/dkh184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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