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Short PNA molecular beacons for real-time PCR allelic discrimination of single nucleotide polymorphisms.

Molecular and cellular probes - 1 Apr 2004

Petersen Kenneth, Vogel Ulla, Rockenbauer Eszter, Nielsen Kirsten Vang, Kølvraa Steen, Bolund Lars, Nexø Bjørn

Abstract excerpt

The typing of a single nucleotide polymorphism with DNA probes is sometimes problematic because of the limited discriminating power of long DNA probes. As an alternative to existing assays, we have developed a real-time PCR assay for the genotyping of single nucleotide polymorphisms using short peptide nucleic acid (PNA) molecular beacons. A single nucleotide polymorphism in exon 6 of the XPD gene was chosen as...

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Identifiers

PMID: 15051121
DOI: 10.1016/j.mcp.2003.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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