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Article

Upregulation of the Hsp104 chaperone at physiological temperature during recovery from thermal insult.

Molecular microbiology - 1 Apr 2004

Seppä Laura, Hänninen Anna-Liisa, Makarow Marja

Abstract excerpt

Thermal insult at 50 degrees C causes protein denaturation in yeast, but the cells survive if preconditioned at 37 degrees C. Survival depends on refolding of heat-denatured proteins. Refolding of cytoplasmic proteins requires Hsp104, the expression of which increases several-fold upon shift of the cells from physiological temperature 24 degrees C to 37 degrees C. We describe here a novel type of regulation of...

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Source

Identifiers

PMID: 15049822
DOI: 10.1111/j.1365-2958.2003.03959.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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