Article
Transforming growth factor-beta 1 production is correlated with genetically determined ACE expression in congenic rats: a possible link between ACE genotype and diabetic nephropathy.
Diabetes - 1 Apr 2004
Pueyo Maria E, Challah Mireille, Gauguier Dominique, Louedec Liliane, Philippe Monique, Gaertner Roger, Marre Michel, Michel Jean-Baptiste, Jacob Marie-Paule
Abstract excerpt
Genetic background appears to modulate the development of diabetic vascular complications. In particular, polymorphisms in the ACE gene have been associated with diabetic nephropathy and, in some studies, macrovascular complications. However, the links between ACE gene polymorphism and factors im...
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