Article
Angiotensin I-converting enzyme: a pathogenetic role in diabetic renal damage?
Current diabetes reviews - 1 Feb 2007
Lely A Titia, Luik Peter T, Navis Gerjan
Abstract excerpt
The renin-angiotensin aldosterone system (RAAS) is well-established to be involved in diabetic nephropathy. Several abnormalities in the RAAS have been described in diabetes mellitus, including an abnormal aldosterone to renin ratio, elevated angiotensin I-converting enzyme (ACE) levels, and altered angiotensin II sensitivity. Whereas the renoprotective properties of ACE-inhibition in diabetic nephropathy have...
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