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Article

Analysis of vitamin D‐regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays

22 Dec 2003

Abstract excerpt

BACKGROUND: 1,25-dihydroxyvitamin D(3) [1,25(OH)2D3] exerts growth inhibitory, pro-differentiating, and pro-apoptotic effects on prostate cells. To better understand the molecular mechanisms underlying these actions, we employed cDNA microarrays to study 1,25(OH)2D3-regulated gene expression in the LNCaP human prostate cancer cells. METHODS: mRNA isolated from LNCaP cells treated with vehicle or 50 nM 1,25(OH)2D3...

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PMID: 15042599
DOI: 10.1002/pros.20006

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