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Article

Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes.

Molecular endocrinology (Baltimore, Md.) - 1 Nov 2005

Wang Tian-Tian, Tavera-Mendoza Luz Elisa, Laperriere David, Libby Eric, MacLeod Naomi Burton, Nagai Yoshihiko, Bourdeau Veronique, Konstorum Anna, Lallemant Benjamin, Zhang Rui, Mader Sylvie, White John H

Abstract excerpt

1alpha,25-Dihydroxyvitamin D3 [1,25(OH)2D3] regulates calcium homeostasis and controls cellular differentiation and proliferation. The vitamin D receptor (VDR) is a ligand-regulated transcription factor that recognizes cognate vitamin D response elements (VDREs) formed by direct or everted repeats of PuG(G/T)TCA motifs separated by 3 or 6 bp (DR3 or ER6). Here, we have identified direct 1,25(OH)2D3 target genes...

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Identifiers

PMID: 16002434
DOI: 10.1210/me.2005-0106

Genes

VDR
TRPV6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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