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Article

v-rasH expression confers hormone-independent in vitro growth to LNCaP prostate carcinoma cells.

Molecular endocrinology (Baltimore, Md.) - 1 Feb 1991

Voeller H J, Wilding G, Gelmann E P

Abstract excerpt

The LNCaP human prostate cancer cell line is dependent on androgen for in vitro growth. To discover genes that may be responsible for progression of prostate cancer from hormone dependence to hormone independence, we transfected LNCaP cells with expression vectors that contained either the v-rasH or c-rasH gene under the control of the cadmium (Cd2+)-inducible human metallothionein-IIA promoter. Numerous...

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PMID: 2038342
DOI: 10.1210/mend-5-2-209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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