Article
The hydrophobic domain of the Mycobacterial Erp protein is not essential for the virulence of Mycobacterium tuberculosis.
Infection and immunity - 1 Apr 2004
Kocíncová Dana, Sondén Berit, Bordat Yann, Pivert Elisabeth, de Mendonça-Lima Leila, Gicquel Brigitte, Reyrat Jean-Marc
Abstract excerpt
Erp (exported repetitive protein) is a member of a mycobacterium-specific family of extracellular proteins. A hydrophobic region that is localized at the C-terminal domain and that represents a quarter of the protein is highly conserved across species. Here we show that this hydrophobic region is not essential for restoring the virulence and tissue damage of an erp::aph mutant strain of M. tuberculosis as...
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