Article
Co-expression of DevR and DevR(N)-Aph proteins is associated with hypoxic adaptation defect and virulence attenuation of Mycobacterium tuberculosis.
PloS one - 26 Feb 2010
Majumdar Shyamasree De, Sharma Deepak, Vashist Atul, Kaur Kohinoor, Taneja Neetu Kumra, Chauhan Santosh, Challu Vijay K, Ramanathan V D, Balasangameshwara V, Kumar Prahlad, Tyagi Jaya Sivaswami
Abstract excerpt
BACKGROUND: The DevR response regulator is implicated in both hypoxic adaptation and virulence of Mycobacterium tuberculosis (M. tb). DevR regulon genes are powerfully induced in vivo implicating them in bacterial adaptation to host control strategies. A better understanding of DevR function will...
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