An infectious aetiology for childhood acute leukaemia: a review of the evidence.

doi:10.1111/j.1365-2141.2004.05166.x

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Article

An infectious aetiology for childhood acute leukaemia: a review of the evidence.

British journal of haematology - 1 Nov 2004

McNally Richard J Q, Eden Tim O B

Abstract excerpt

There are three current hypotheses concerning infectious mechanisms in the aetiology of childhood leukaemia: exposure in utero or around the time of birth, delayed exposure beyond the first year of life to common infections and unusual population mixing. No specific virus has been definitively linked with childhood leukaemia and there is no evidence to date of viral genomic inclusions within leukaemic cells. The...

Topics

Breast Feeding
Case-Control Studies
Child
Child, Preschool
Female
Genetic Predisposition to Disease
Humans
Immune System
Parents
Population Dynamics
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pregnancy
Prenatal Exposure Delayed Effects
Risk Factors
Social Environment
Vaccination

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Identifiers

PMID: 15491284
DOI: 10.1111/j.1365-2141.2004.05166.x

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