Article
Influence of CYP2C19 functional polymorphism on Helicobacter pylori eradication.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Mar 2010
Ozdil Burhan, Akkiz Hikmet, Bayram Süleyman, Bekar Aynur, Akgöllü Ersin, Sandikçi Macit
Abstract excerpt
BACKGROUND/AIMS: Proton pump inhibitors are mainly metabolized by cytochrome P450 2C19 in the liver. Recently, some studies have shown that the acid suppressing effect of proton pump inhibitors are influenced by a functional polymorphism of cytochrome P450 2C19. The aim of the present study was to investigate the effect of cytochrome P450 2C19 polymorphism on Helicobacter pylori eradication in patients who...
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