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Article

Identification of critical residues required for the mutation avoidance function of human MutY (hMYH) and implications in colorectal cancer.

Cancer letters - 8 Mar 2004

Wooden Steven H, Bassett Heather M, Wood Thomas G, McCullough Amanda K

Abstract excerpt

Mutations found in human tumors often include transversions of GC to TA that may result from the mis-pairing of 8-oxoG with adenine during DNA replication. The human MutY (hMYH) enzyme, an adenine-specific DNA glycosylase, initiates repair at this mismatch. It has recently been demonstrated that...

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Identifiers

PMID: 15036665
DOI: 10.1016/j.canlet.2003.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15036665-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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