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Primer extension assay for prion protein genotype determination in sheep.

Molecular and cellular probes - 1 Feb 2004

Vaccari G, Conte M, Morelli L, Di Guardo G, Petraroli R, Agrimi U

Abstract excerpt

Scrapie is a transmissible spongiform encephalopathy (TSE) which affects sheep and goats. TSEs are characterised by the conversion of the cellular prion protein (PrP(C)) into the pathological form PrP(Sc). The occurrence of scrapie in sheep is influenced by polymorphisms in the PrP gene; in particular, three codons (136, 154 and 171) are important in conditioning the susceptibility/resistance of sheep to the...

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Identifiers

PMID: 15036367
DOI: 10.1016/j.mcp.2003.06.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Primer extension assay for prion protein genotype determination in sheep.PMID 15036367Read ↗

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A dual fluorescent multiprobe assay for prion protein genotyping in sheep.Semantic proximity Read ↗

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