Article
Primer extension assay for prion protein genotype determination in sheep.
Molecular and cellular probes - 1 Feb 2004
Vaccari G, Conte M, Morelli L, Di Guardo G, Petraroli R, Agrimi U
Abstract excerpt
Scrapie is a transmissible spongiform encephalopathy (TSE) which affects sheep and goats. TSEs are characterised by the conversion of the cellular prion protein (PrP(C)) into the pathological form PrP(Sc). The occurrence of scrapie in sheep is influenced by polymorphisms in the PrP gene; in parti...
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