Article
[Association between CCND1 polymorphisms and chromosomal damage among workers exposed to 1,3-butadiene].
Wei sheng yan jiu = Journal of hygiene research - 1 Mar 2015
Liu Nan, Li Bin, Cheng Juan, Zheng Guoying, Li Yun, Guan Weijun
Abstract excerpt
OBJECTIVE: To investigate the association between CCND1 polymorphisms and the DNA and chromosome damage in peripheral blood lymphocytes among workers exposed to 1,3-butadiene(BD). METHODS: 171 workers exposed to 1,3-butadiene and 55 controls without occupational BD exposure were investigated. Cytokinesis-block micronucleus(CBMN) detection and comet assay were used to evaluate the chromosomal and DNA damage levels...
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