Article
RISC assembly defects in the Drosophila RNAi mutant armitage.
Cell - 19 Mar 2004
Tomari Yukihide, Du Tingting, Haley Benjamin, Schwarz Dianne S, Bennett Ryan, Cook Heather A, Koppetsch Birgit S, Theurkauf William E, Zamore Phillip D
Abstract excerpt
The putative RNA helicase, Armitage (Armi), is required to repress oskar translation in Drosophila oocytes; armi mutant females are sterile and armi mutations disrupt anteroposterior and dorsoventral patterning. Here, we show that armi is required for RNAi. armi mutant male germ cells fail to sil...
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