ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene.

doi:10.1016/j.ijcard.2013.12.084

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Article

ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene.

International journal of cardiology - 15 Feb 2014

Hu Dan, Barajas-Martínez Hector, Terzic Andre, Park Sungjo, Pfeiffer Ryan, Burashnikov Elena, Wu Yuesheng, Borggrefe Martin, Veltmann Christian, Schimpf Rainer, Cai John J, Nam Gi-Byong, Deshmukh Pramod, Scheinman Melvin, Preminger Mark, Steinberg Jonathan, López-Izquierdo Angélica, Ponce-Balbuena Daniela, Wolpert Christian, Haïssaguerre Michel, Sánchez-Chapula José Antonio, Antzelevitch Charles

Abstract excerpt

BACKGROUND: Genetic defects in KCNJ8, encoding the Kir6.1 subunit of the ATP-sensitive K(+) channel (I(K-ATP)), have previously been associated with early repolarization (ERS) and Brugada (BrS) syndromes. Here we test the hypothesis that genetic variants in ABCC9, encoding the ATP-binding cassette transporter of IK-ATP (SUR2A), are also associated with both BrS and ERS. METHODS AND RESULTS: Direct sequencing of...

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Identifiers

PMID: 24439875
DOI: 10.1016/j.ijcard.2013.12.084
PMCID: PMC3947869

Genes

ABCC9
KCNJ8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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