Article
SNP analysis combined with protein structure prediction defines structure-functional relationships in cancer related cytochrome P450 estrogen metabolism.
Current medicinal chemistry - 1 Mar 2004
Tsigelny Igor F, Kotlovyi Vladimir, Wasserman Linda
Abstract excerpt
The P450 family of proteins has more than 1000 representatives, which despite sometimes relatively low sequence identity have a surprisingly high level of structural similarity. This fact makes this family of proteins ideal candidate for various types of modeling based on protein structure predic...
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