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Article

Tissue plasminogen activator -7351C/T enhancer polymorphism is a risk factor for lacunar stroke.

Stroke - 1 May 2004

Jannes Jim, Hamilton-Bruce Monica A, Pilotto Louis, Smith Brian J, Mullighan Charles G, Bardy Peter G, Koblar Simon A

Abstract excerpt

BACKGROUND AND PURPOSE: Occlusive thrombosis is an important component of small- and large-vessel ischemic stroke. Endogenous tissue plasminogen activator (TPA) is the primary mediator of intravascular fibrinolysis and is predominantly expressed by the endothelium of small vessels. The acute rele...

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Identifiers

PMID: 15031453
DOI: 10.1161/01.STR.0000124123.76658.6c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15031453-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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