Article
Single nucleotide polymorphism of CD40 in the 5'-untranslated region is associated with ischemic stroke.
Gene - 25 Oct 2013
Ma Ying, Wang Shun-Xian, Liu Yun, Peng Guo-Guang, Wang Xiao-Ming, Zhang Bo, Wu Bi-Hua, Yu Ju-Ming
Abstract excerpt
OBJECTIVES: Ischemic stroke is influenced by both environmental and genetic factors. The CD40/CD40L system is related to proinflammatory and prothrombogenic responses, which are involved in the pathophysiology of ischemic stroke. The aim of this study was to evaluate association between the CD40 -1C/T single nucleotide polymorphism (SNP) and ischemic stroke in a Chinese population. METHODS: We conducted a...
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