Article
Decreased frequency of the TNF2 allele of TNF-alpha -308 promoter polymorphism is associated with lacunar infarction.
Cytokine - 21 Jan 2006
Harcos Péter, Laki Judit, Kiszel Petra, Széplaki Zoltán, Szolnoki Zoltán, Kovács Margit, Melegh Béla, Széplaki Gábor, Füst George, Blaskó Bernadett
Abstract excerpt
BACKGROUND AND PURPOSE: Enhanced release of proinflammatory cytokines may contribute to the pathogenesis of stroke. It was examined whether G to A promoter polymorphism in the tumor necrosis factor-alpha gene at position -308 affects the risk of stroke. METHODS: We genotyped 336 patients with ischemic stroke and 333 healthy controls for this polymorphism. Patients were divided into different groups based on the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
