Article
Tissue angiotensin-converting enzyme in imposed and physiological flow-related arterial remodeling in mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 2004
Hilgers Rob H P, Schiffers Paul M H, Aartsen Wendy M, Fazzi Gregorio E, Smits Jos F M, De Mey Jo G R
Abstract excerpt
OBJECTIVE: To test whether membrane-bound angiotensin I-converting enzyme (t-ACE) is involved in arterial remodeling, we applied unilateral carotid artery (CA) ligation and studied uterine arteries (UA) before, during, and after pregnancy in t-ACE-/- and t-ACE+/+ mice. RESULTS- In CA of t-ACE-/-...
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