Article
Feto- and utero-placental vascular adaptations to chronic maternal hypoxia in the mouse.
The Journal of physiology - 1 Aug 2018
Cahill Lindsay S, Rennie Monique Y, Hoggarth Johnathan, Yu Lisa X, Rahman Anum, Kingdom John C, Seed Mike, Macgowan Christopher K, Sled John G
Abstract excerpt
KEY POINTS: Chronic fetal hypoxia is one of the most common complications of pregnancy and is known to cause fetal growth restriction. The structural adaptations of the placental vasculature responsible for growth restriction with chronic hypoxia are not well elucidated. Using a mouse model of chronic maternal hypoxia in combination with micro-computed tomography and scanning electron microscopy, we found several...
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