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Article

Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate.

European journal of biochemistry - 1 Apr 2004

Stojan Jure, Brochier Laure, Alies Carole, Colletier Jacques Philippe, Fournier Didier

Abstract excerpt

Acetylcholine hydrolysis by acetylcholinesterase is inhibited at high substrate concentrations. To determine the residues involved in this phenomenon, we have mutated most of the residues lining the active-site gorge but mutating these did not completely eliminate hydrolysis. Thus, we analyzed th...

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Identifiers

PMID: 15030487
DOI: 10.1111/j.1432-1033.2004.04048.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15030487-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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