Article
Angiotensin receptor blockers in diabetic nephropathy: renal and cardiovascular end points.
Seminars in nephrology - 1 Mar 2004
Parving Hans-Henrik, Andersen Steen, Jacobsen Peter, Christensen Per K, Rossing Kasper, Hovind Peter, Rossing Peter, Tarnow Lise
Abstract excerpt
The activity of the renin-angiotensin-aldosterone system (RAAS) is elevated both in the circulation and in the renal tissue of diabetic and nondiabetic nephropathies. The increased RAAS activity plays an important role in the hemodynamic and nonhemodynamic pathogenetic mechanisms involved in kidney disease. Previous studies have demonstrated that albuminuria is not only a marker of glomerular lesions, but also a...
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