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Article

Poorer cognitive performance in humans with mild cognitive impairment carrying the T variant of the Glu/Asp NOS3 polymorphism.

Neuroscience letters - 18 Mar 2004

Solé-Padullés Cristina, Bartrés-Faz David, Junqué Carme, Via Marc, Matarín Mar, González-Pérez Emili, Moral Pedro, Moya Antoni, Clemente Immaculada C

Abstract excerpt

Mild cognitive impairment (MCI) is a transitional state between normal aging and Alzheimer's disease (AD) and is a high-risk condition for dementia. The endothelial nitric oxide synthase (NOS3) gene encodes endothelial NOS, an enzyme that regulates the production of the vasodilatory nitric oxide associated with the cerebral small vessel pathology observed in early AD. We studied the distribution of genotype and...

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Identifiers

PMID: 15016421
DOI: 10.1016/j.neulet.2003.12.044

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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