Article
Genetic association between endothelial nitric oxide synthase and Alzheimer disease.
Clinical genetics - 1 Jul 2006
Akomolafe A, Lunetta K L, Erlich P M, Cupples L A, Baldwin C T, Huyck M, Green R C, Farrer L A
Abstract excerpt
Evidence suggests that vascular and inflammatory factors may be important in the etiology of Alzheimer disease (AD). The Glu/Glu genotype at the Glu298Asp variant of the endothelial nitric oxide synthase (NOS3) gene has been tested for association with AD in several Caucasian and Asian populations, with conflicting results. We tested the Glu298Asp variant for association in African American and Caucasian AD...
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