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Article

NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors.

Neurobiology of aging - 1 Mar 2011

Morris Christopher M, Ballard Clive G, Allan Louise, Rowan Elise, Stephens Sally, Firbank Michael, Ford Gary A, Kenny Rose Anne, O'Brien John T, Kalaria Raj N

Abstract excerpt

Stroke is a major risk factor for the development of dementia in the elderly. It is unclear which genes influence risk of delayed dementia after stroke. We tested a single nucleotide polymorphism (SNP) in endothelial nitric oxide synthase (NOS3) gene at codon 298 (single-nucleotide polymorphism rs1799983; p.Asp298Glu) in a cohort of 355 older (>75 years) stroke survivors, who had detailed cognitive assessments...

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Source

Identifiers

PMID: 20691505
DOI: 10.1016/j.neurobiolaging.2010.06.012

Genes

NOS3
APOE

Variants

rs1799983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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