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Article

Association between Alzheimer's disease and the NOS3 gene Glu298Asp polymorphism in Chinese.

Journal of molecular neuroscience : MN - 1 Feb 2008

Wang Binbin, Tan Sainan, Yang Ze, Xie Yan-Chen, Wang Jing, Zhou Sirui, Li Shu, Zheng Chenguang, Ma Xu

Abstract excerpt

The oxidative stress caused by nitric oxide (NO) in the brain has been proposed as a pathogenic mechanism in Alzheimer's disease. Endothelial NO synthase (ecNOS) produces the majority of circulating NO. The biological functional and genetic association studies suggested that the Glu298Asp polymorphism of the ecNOS gene (NOS3) may be a genetic risk factor for late-onset Alzheimer's disease (LOAD). To investigate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18183499
DOI: 10.1007/s12031-007-9026-6

Genes

APOE
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between Alzheimer's disease and the NOS3 gene Glu298Asp polymorphism in Chinese.PMID 18183499Read ↗

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Association between Alzheimer's disease and the NOS3 gene.Semantic proximity Read ↗

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Association of the endothelial nitric oxide synthase (NOS3) Glu298Asp gene polymorphism with the risk of Alzheimer's disease-- a meta-analysis.Semantic proximity Read ↗

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