Article
Single nucleotide polymorphisms in breast cancer.
Oncology reports - 1 Apr 2004
Försti Asta, Angelini Sabrina, Festa Fabiola, Sanyal Somali, Zhang Zhenzhong, Grzybowska Ewa, Pamula Jolanta, Pekala Wioletta, Zientek Helena, Hemminki Kari, Kumar Rajiv
Abstract excerpt
A limited number of genes have been identified that explain heritable risks of breast cancer (BC). We searched for low-penetrant genes in an association study using two populations: 223 Finnish unselected patients and 172 Polish familial cases, both with locally collected healthy controls. Candidate genes included DNA repair genes, methylenetetrahydrofolate reductase (MTHFR) and cyclin D1 genes. The frequencies...
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