Article
Identification of two novel single nucleotide polymorphisms in the promoter of the human interleukin-18 receptor alpha.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Feb 2004
Cardoso S P, Keen L, Bidwell J
Abstract excerpt
Single-strand conformational polymorphism (SSCP) was used to identify single nucleotide polymorphisms (SNPs) in the promoter region of the human interleukin-18 receptor alpha (IL-18Ralpha). Two SNPs were identified at positions -69 and -638 relative to the transcriptional start site. Two-way comparison of the two SNPs revealed strong linkage disequilibrium (chi2 = 63.45, P < 0.001). Three haplotypes were...
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