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Article

Aggregation of thyroid autoantibodies in first‐degree relatives of patients with autoimmune thyroid disease is mainly due to genes: a twin study

19 Jan 2004

Abstract excerpt

BACKGROUND: Family studies have repeatedly shown aggregation of thyroid autoantibodies to thyroid peroxidase (TPOab) and thyroglobulin (Tgab) in first-degree relatives of patients with autoimmune thyroid disease (AITD). This phenomenon has generally been interpreted as evidence of a genetic component in the development of thyroid autoantibodies. However, family studies cannot determine whether the observed...

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PMID: 15008998
DOI: 10.1111/j.1365-2265.2004.01983.x

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