Article
Early immune responses and parasite tissue distribution in mice experimentally infected with oocysts of either archetypal or non-archetypal genotypes of Toxoplasma gondii.
Parasitology - 1 Apr 2021
Chiebao Daniela P, Bartley Paul M, Chianini Francesca, Black Lauren E, Burrells Alison, Pena Hilda F J, Soares Rodrigo M, Innes Elisabeth A, Katzer Frank
Abstract excerpt
In most of the world Toxoplasma gondii is comprised of archetypal types (types I, II and III); however, South America displays several non-archetypal strains. This study used an experimental mouse model to characterize the immune response and parasite kinetics following infection with different parasite genotypes. An oral inoculation of 50 oocysts per mouse from T. gondii M4 type II (archetypal, avirulent), BrI...
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