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Article

A rapid method of screening for N-acetyltransferase (NAT2) phenotype by use of the WAVE DNA fragment analysis system.

Biochemical genetics - 1 Dec 2003

Osborne Aileen, Bell Christine, Grant Faye, Dick Finlay, Seaton Anthony, Haites Neva

Abstract excerpt

N-Acetyltransferase 2 (NAT2) is involved in Phase II biotransformation of a variety of toxicants. Polymorphisms in the NAT2 gene result in a slow acetylator phenotype, which has been associated with various cancers and neurodegenerative diseases. To date most studies investigating NAT2 genotype/phenotype have adopted an RFLP approach, which is both expensive and time-consuming. Using the Wave DNA fragment...

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Share to Arylamine N-Acetyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heteroduplex Analysis

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Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Share to Sequence Analysis, DNA

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Source

Identifiers

PMID: 14994828
DOI: 10.1023/b:bigi.0000007775.61514.e8

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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