Article
Characterization of a five-gene cluster required for the biogenesis of type 4 fimbriae in Pseudomonas aeruginosa.
Molecular microbiology - 1 May 1995
Martin P R, Watson A A, McCaul T F, Mattick J S
Abstract excerpt
The opportunistic pathogen Pseudomonas aeruginosa produces type 4 fimbriae which promote adhesion to epithelial cells and are associated with a form of surface translocation called twitching motility. Transposon mutagenesis was used to identify loci required for fimbrial assembly or function by screening for mutants that lack the spreading colony morphology characteristic of twitching motility. Six mutants were...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Carrier Proteins
- Chromosome Mapping
- Chromosomes, Bacterial
- Cloning, Molecular
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- Genes, Bacterial