Article
Interaction between smoking and glutathione S-transferase polymorphisms in solvent-induced chronic toxic encephalopathy.
Toxicology and industrial health - 1 Jul 2002
Ahmadi Ahmad, Jönsson Pia, Flodin Ulf, Söderkvist Peter
Abstract excerpt
Exposure to organic solvents is still common in industrial and other work environments, and increases the risk of chronic toxic encephalopathy (CTE). Genetic variation in metabolic enzymes for solvents and other xenobiotics may modify the risk of developing toxic effects. Therefore, we investigated the presence of null genotypes for glutathione S-transferases M1 and T1 (GSTM1, GSTT1) and two genetic polymorphisms...
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