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Article

Specific mutations of hepatitis B virus in plasma predict liver cancer development.

Proceedings of the National Academy of Sciences of the United States of America - 9 Mar 2004

Kuang Shuang-Yuan, Jackson Peta E, Wang Jin-Bing, Lu Pei-Xing, Muñoz Alvaro, Qian Geng-Sun, Kensler Thomas W, Groopman John D

Abstract excerpt

A major risk factor for hepatocellular carcinoma (HCC) is hepatitis B virus (HBV), whose pathogenesis is exacerbated by the acquisition of mutations that accelerate carcinogenesis. We examined, with mass spectrometry, the temporality of an HBV 1762(T)/1764(A) double mutation in plasma and tumors....

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14990795
DOI: 10.1073/pnas.0308232100
PMCID: PMC373504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14990795-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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