Article
Predictive power of hepatitis B 1762T/1764A mutations in plasma for hepatocellular carcinoma risk in Qidong, China.
Carcinogenesis - 1 Jun 2011
Muñoz Alvaro, Chen Jian Guo, Egner Patricia A, Marshall Melinda L, Johnson Jamie L, Schneider Michael F, Lu Jian Hua, Zhu Yuan Rong, Wang Jin-Bing, Chen Tao Yang, Kensler Thomas W, Groopman John D
Abstract excerpt
Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with nearly 700,000 deaths occurring annually. Hepatitis B virus (HBV) is a major contributor to HCC and acquired mutations in the HBV genome may accelerate its pathogenesis. In this study, a matched case-control investigation of 345 men who died of HCC and 625 controls were nested within a cohort of male hepatitis B surface antigen (HBsAg)...
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