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Article

Actin- and tubulin-dependent functions during Saccharomyces cerevisiae mating projection formation.

Molecular biology of the cell - 1 Apr 1992

Read E B, Okamura H H, Drubin D G

Abstract excerpt

Several conditional-lethal mutant alleles of the single-copy Saccharomyces cerevisiae beta-tubulin and actin genes were used to evaluate the roles of microtubules and actin filaments in the pheromone-induced extension of mating projections. Mutants defective in tubulin assembly form projections indistinguishable in appearance from those formed by wild-type cells. However, the tubulin mutants are unable to move...

Topics

Actins
Cell Nucleus
Cell Polarity
Conjugation, Genetic
Cytoskeleton
Fluorescent Antibody Technique
Microtubules
Morphogenesis
Mutation
Saccharomyces cerevisiae
Sex Attractants

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Tubulin

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Identifiers

PMID: 1498363
DOI: 10.1091/mbc.3.4.429
PMCID: PMC275593

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1498363-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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