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Article

Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor.

Thrombosis and haemostasis - 1 Mar 2004

Raab Sabine, Beck Heike, Gaumann Andreas, Yüce Ali, Gerber Hans-Peter, Plate Karl, Hammes Hans-Peter, Ferrara Napoleone, Breier Georg

Abstract excerpt

Vascular endothelial growth factor (VEGF) is essential for the differentiation of the primitive embryonic vascular system and has been implicated in the vascularization of organs. Recently, VEGF has also been proposed to play a role in neural development, neuroprotection, and adult neurogenesis. Here we have investigated the function of VEGF in the developing brain by cre-lox technology. We show that VEGF...

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Identifiers

PMID: 14983237
DOI: 10.1160/TH03-09-0582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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