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Article

Vascular endothelial growth factor (VEGF) isoform regulation of early forebrain development.

Developmental biology - 1 Oct 2011

Darland Diane C, Cain Jacob T, Berosik Matthew A, Saint-Geniez Magali, Odens Patrick W, Schaubhut Geoffrey J, Frisch Sarah, Stemmer-Rachamimov Anat, Darland Tristan, D'Amore Patricia A

Abstract excerpt

This work was designed to determine the role of the vascular endothelial growth factor A (VEGF) isoforms during early neuroepithelial development in the mammalian central nervous system (CNS), specifically in the forebrain. An emerging model of interdependence between neural and vascular systems includes VEGF, with its dual roles as a potent angiogenesis factor and neural regulator. Although a number of studies...

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Identifiers

PMID: 21803034
DOI: 10.1016/j.ydbio.2011.06.045
PMCID: PMC3189089

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