Article
A yeast gene necessary for bud-site selection encodes a protein similar to insulin-degrading enzymes.
Nature - 8 Dec 1994
Fujita A, Oka C, Arikawa Y, Katagai T, Tonouchi A, Kuhara S, Misumi Y
Abstract excerpt
Cells of the yeast Saccharomyces cerevisiae choose bud sites in a non-random spatial pattern that depends on mating type: axial for haploid cells and bipolar for a/alpha diploid cells. We identified a mutant yeast, axl 1, in which the budding pattern is altered from axial to bipolar. Expression of the AXL1 gene is repressed in a/alpha diploid cells. With the ectopic expression of AXL1, a/alpha cells exhibited an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.